Multiple Sclerosis and Lifestyle Challenges

15 05 2011
Challenge yourself to see all that is in the world

Multiple Sclerosis (MS) is a chronic autoimmune disorder and disease that affects the central nervous system.  The immune system somehow identifies and attacks the surrounding nerve cables (axons), leading to inflammation and injury of the brain and spinal cords cable systems.  This has a direct impact on the body’s ability to see, feel, move, and/or loss of muscle control, balance, strength and bodily functions.  When the nervous system experiences this type of damage internally it is much like an electrical wire that shorts to ground.  As your bodies movement is dependent on neuron-electrical paths; if they are compromised, electricity does not go/or not enough, or too much where needed.  When this occurs electrical signals can completely misfire and fire to parts of the body that further complicates and creates other health concerns.

 Symptoms include: Painful muscle spasm, facial pain, numbness, tingling, crawling or burning in any area of body, especially arms, or legs.  Or create problems for any type of movement and/or creates muscle weakness.  Incontinence can occur and/or a need to urinate frequently.  Urination can also be painful or a burning sensation.  Constipation and stool leakage also presents problems for many.  Other symptoms of MS:  Rapid eye movement, eye discomfort in general, or vision loss; decreased reasoning, solving skills, or memory lapses and poor judgment; hearing loss, dizziness, or depression.  To include difficult speech patterns, chewing or swallowing.  Also one can experience problems with erections, or vaginal lubrication. 

    Since the nervous system is our electrical wire way from the brain to the rest of our bodies functional parts; if the damaged myelin sheaths (our bodies nerves insulation) is compromised and shorts to other parts of the body the intended movement does not work according to plan.  As a matter of fact, the compromised electrical neural wire way can create many possible problems throughout the body.  After all, the electrical stimulus response is either voluntary [the brain thinks the movement], or involuntary [independent autonomic nervous system – The brain’s Central Nervous System (CNS) self regulates vital organs outside of our control].

    With MS, movement is now partially, or fully uncontrolled voltage [also called action potential] that may, or may not send electrical voltage to the intended body area.  And voltage leakage from a breach in the neural highways is known as demyelination of the neuron protective sheath.  Much like a conductive wire has a plastic coat around copper wire; neurons have a protective “myelin” sheath to keep the voltage inside the conductive neuron highway.  The myelin sheath ensures the electrical signals from the brain reach the intended body area destination.  MS symptoms worsen when the brain can no longer effectively send signals down through the spinal cord to communicate with distal neuron conductors (long neural pathways, e.g.,  to arms, legs).

To summarize:  When a person is diagnosed with MS, the cause of symptoms is due to the myelin insulation of conductive nerves from the brain to the spinal cord and subordinate neuron systems have developed scars (scleroses, plaques or lesions).  These scars occur when the body’s immune system attacks and damages the body’s protective myelin sheaths (Hence:  Demyelination). 

    To date, there is no cure for MS.  However, if the current treatment offered is followed as prescribed, functionality can be maximized and new attacks can be minimized to slow down the progression of disability(s).  It is also true some patients have very bad tolerance to conventional treatments.  When this is the case other alternative treatments are sought.

    The prognosis of MS is difficult to determine as the progression of this disease on the nervous systems can take one of several subtype courses.

Prognosis & Symptoms:  Some MS patients experience acute flare-ups in hours, or days.  This is referred to as a relapse, or attack.  Many of those that begin to experience MS symptoms include painful eye movement (optic neuritis).  And for others, symptoms may return within weeks, or even years and through time more MS complications arise.  This is called ‘relapsing remitting’.

     A good prognosis of the condition is visual loss, whereas numbness, gait disturbance and weakness are rather poor prognoses.   In other words, a poor prognosis of functional deterioration and life expectancy seems to correlate with numbness, poor gait and balance; where loss of eye sight does not.

     For a period of time during remittance and then relapse; this cycle can occur for years where the patient experiences similar superimposed relapses.  However, through time these superimposed relapse subside slowly and is indicative of a worsening MS condition.  This is called secondary chronic-progressive, or secondary progressive with/without bouts of relapsing remitting superimposed symptoms [which are known as relapsing progressive].

     During the relapsing remitting stage of initial MS disease, the statistical time duration for the need of a wheelchair is 20 years. For primary progressive conditions, a wheelchair will be needed after almost 6-7 years. Physical limitations caused by this condition are seen in about 70% of the patients.

 General MS Stat’s – Symptoms of this neurological disease comes in many forms that appear to come and go at will within the early stages (relapsing forms).  Or the progression can become accumulative over time.  The progressive MS form creates permanent neurological damage for many.  For primary progressive MS there is typically a need after diagnosis for a mobile scooter or wheel chair. 

     Two thirds of MS patients with minimal disability after 5 years will not show deterioration of condition within the following ten years.  Also one in every three patients is able to work 15-20 years before significant disabilities occur.  And 70% of all diagnosed with MS are living 25- 35 years after the diagnosis.   The average life expectancy of those diagnosed live 10-15 years less than those that never acquire the disease.

 Mortality – Ten percent of MS cases flare into chronic progression without relapses from earlier symptoms.  Less than 5% of those with severe progressive MS die within 5 years.  For most with MS, they live fairly normal lives and suffer bouts of relapsing remitting conditions that can be controlled with treatment. Up to 20% of those diagnosed with MS have a slow, to no progression of symptoms.   Although this disease does impact men, it is most prominent in young adults and women.  For most deaths regarding our youth after MS diagnosis, death appears to be from suicide.

 Treatment & Lifestyle – The statistical data provided was acquired before the introduction of immunomodulatory drugs 10 years ago. The advent of these drugs has delayed the progression for patients over several years. A lot of research, clinical study and experiments are being carried out on a continuous basis for multiple sclerosis prevention.  At present there are no clinically established laboratory research details available for present prognosis in multiple sclerosis.   However, it appears if you acquire MS the majority will live full productive quality lifestyles with varying disability challenges.

 Internet References:

http://health.yahoo.net/channel/multiple-sclerosis-ms_symptoms

http://www.mayoclinic.org/multiple-sclerosis/

http://www.buzzle.com/articles/multiple-sclerosis-prognosis.html

http://en.wikipedia.org/wiki/Multiple_schlerosis

Marc T. Woodard, MBA, BS Exercise Science, USA Medical Services Officer, CPT, RET.  2011 Copyright, All rights reserved, Mirror Athlete Publishing @: http://www.mirrorathlete.com,  Sign up for your Free eNewsletter.





Medical Marijuana & Pain Relief, Scientific Support Data

19 05 2009

    Below are citations with appropriate references to give credit to those that have provided medical marijuana research data information with unique supporting and correlated data.  It appears obvious, or apparent within these controlled studies and citations, cannabis shows a unique medicinal composition with unique pain blocking properties that could replace in part, or whole other pain management prescriptions without the additional pharmaceutical health risks.  Standard prescription medications or outpatient services that ease pain, spasms and inflammation may be accomplished through medical marijuana use at a fraction of the cost.  The Compassionate Use Act, 1996 was established to provide physicians the ability to recommend chronic pain patients medical marijuana at first for cancer patients.  Through years of research science is seeing a whole range of potential use for cannabis as an alternative treatment for many types of chronic pain disease.

“Persistent and disabling pain can have numerous and sometimes multiple causes, including cancer; AIDS; sickle cell anemia; glaucoma, cancer, shingles, multiple sclerosis; defects or injuries to the back, neck and spinal cord; arthritis and other rheumatic and degenerative hip, joint and connective tissue disorders; and severe burns.  Pain is not a primary condition or injury, but rather a severe, frequently intolerable symptom that varies in frequency, duration, and severity according to the individual (Chronic Pain and Medical Marijuana, ASA PDF Brochure# 888-929-436.  See end of article for brochure details).

“A recent study conducted at University of California at Davis, 17 April 2008, 38 patients experiencing neuropathic pain from varying diseases; diabetes, spinal cord injuries, multiple sclerosis, epilepsy, chronic pain, HIV/AIDS-related neuropathy, etc., were given marijuana cigarettes, some patients with zero% THC, 3.5% and 7%.  Students through each session took the same number of puffs to ensure uniformity.  Thereafter, it was determined marijuana reduced pain intensity significantly over a 5 hour period/per trial.  It should also be noted, memory tests and cognitive skills appeared to decline, but not more, or less significantly than narcotic pain killers (Complete Study, Contact MPP “Marijuana Policy Project Director of communications Bruce Mirken, 202-215-4205, or visit http://MarijuanaPolicy.org).”

“The smoking of cannabis, even long term, is not harmful to health….”  So began a 1995 editorial statement of Great Britain’s leading medical journal, The Lancet.  The long history of human use of cannabis also attests to its safety—nearly 5,000 years of documented use without a single death.”

“Substances similar to or derived from marijuana could benefit more than 97 million Americans who experience some form of pain each year (U.S. Society for Neuroscience, 1997).”

“The role that cannabis can play in treating chronic pain.  After nausea and vomiting, chronic pain was the condition cited most often to the IOM (Institute of Medicine) study team as a medicinal use for marijuana.”The study found that “basic biology indicates a role for cannabinoids [a group of compounds found in cannabis] in pain and control of movement, which is consistent with a possible therapeutic role in these areas. The evidence is relatively strong for the treatment of pain and intriguingly, although less well established, for movement disorder (Commissioned Study by the White House, by the Institute of Medicine, 1999).”

“Inhaled cannabis provides almost immediate relief with significantly fewer adverse effects than orally ingested Marinol (the only legal THC hemp extract pharmaceutical, DEA Class III authorized drug schedule prescription).  Inhalation allows the active compounds in cannabis to be absorbed into the blood stream with greater speed and efficiency. It is for this reason that inhalation is an increasingly common, and often preferable, route of administration for many medications.

“One problem with cannabinoids is that they are very fat-soluble, so that makes them very difficult to formulate the drugs into pills or injections.  One way that’s being looked at by some pharmaceutical companies is using the kind of inhaler that asthma sufferers use.” Smoking is obviously a big health hazard and scientists are looking at ways of delivering the drug to the body (ASA Americans for Safe Access, www.AmericansForSafeAccess.org).”

“Cannabis may also be more effective than Marinol because it contains many more cannabinoids than just the THC that is Marinol’s active ingredient. The additional cannabinoids may well have additional and complementary antiemetic (effective against vomiting and nausea) qualities. They have been conclusively shown to have better pain-control properties when taken in combination than THC alone (U.S. Society for Neuroscience Conclusion).”

    “The Compassionate Use Act passed in 1996 expressly provides that “chronic pain” is a condition for which physicians are authorized to recommend marijuana without threat or fear of punishment for providing a full range of treatment modalities to care for patients in pain.  However, Federal policy on medical cannabis is filled with contradictions.  Cannabis is a Schedule I drug, classified as having no medicinal value and a high potential for abuse, yet its most psychoactive component, THC, is legally available as Marinol and is listed in DEA Drug Schedule III Classification for physician prescriptions.  For those that don’t know, Class III prescriptions fall under the same legal prescribed DEA classification, such as Tylenol.  To add insult to injury an average month supply of Marinol will cost you ~$500.00.  A medical marijuana script-license provides you the right to produce and self medicate without the outrageous cost to alleviate chronic pain but has a double jeopardy possibility of imprisonment at the federal government’s discretion!  Is the government trying to figure out a way to make money by controlling a multi-billion dollar industry at the expense of suffering people in pain?  How much lower could we stoop as a nation?

    Currently, laws that effectively remove state-level criminal penalties for growing and/or possessing medical cannabis are in place in Alaska, California, Colorado, Hawaii, Maine, Maryland, Montana, Nevada, Oregon, Rhode Island, Vermont and Washington.  Thirty-six states have symbolic medical cannabis laws (laws that support medical cannabis but do not provide patients with legal protection under state law).  Reference,  Compassionate Use Act, 1996 – Key organizations; Drug Enforcement Administration, (DEA) Federal Department of Health and Human Services (HHS), and the Food and Drug Administration (FDA), Americans For Safe Access (ASA).

“By comparison, the side effects associated with cannabis are typically mild and are classified as “low risk.” Euphoric mood changes are among the most frequent side effects. Cannabinoids can exacerbate schizophrenic psychosis in predisposed persons. Cannabinoids impede cognitive and psychomotor performance, resulting in temporary impairment. Chronic use can lead to the development of tolerance. Tachycardia and hypotension are frequently documented as adverse events in the cardiovascular system. A few cases of myocardial ischemia have been reported in young and previously healthy patients. Inhaling the smoke of cannabis cigarettes induces side effects on the respiratory system. Cannabinoids are contraindicated for patients with a history of Cardiac ischemia.  In summary, a low risk profile is evident from the literature available. Serious complications are very rare and are not usually reported during the use of cannabinoids for medical indications (Chronic Pain and Medical Marijuana, ASA PDF Brochure# 888-929-4367).”

“Institute of Medicine, “Nausea, appetite loss, pain and anxiety… All can be mitigated by marijuana… For patients, such as those with AIDS or undergoing chemotherapy, who suffer simultaneously from severe pain, nausea, and appetite loss, cannabinoid drugs might offer broad spectrum relief not found in any other single medication (Marijuana and Medicine; Assessing the Science Base, 1999).”

“Where morphine fails, marijuana may work. That’s the major finding of British research into the pain caused by nerve injuries, a pain known to be somewhat resistant to morphine and similar drugs that are the gold standard for treating just about any other kind of serious pain.  It’s known that if you injure a nerve, the morphine receptors in the spinal cord disappear and that’s probably why morphine isn’t a very effective pain killer for such conditions as shingles, people who have had an amputation or perhaps if cancer has invaded the spinal cord (Molecular and Cellular Neuroscience Report & London’s Imperial College, Andrew Rice).”

“One of marijuana’s greatest advantages as a medicine is its remarkable safety. It has little effect on major physiological functions.  There is no known case of a lethal overdose; on the basis of Animal models, the ratio of lethal to effective dose is estimated as 40,000 to 1. By comparison, the ratio is between 3 and 50 to 1 for Secobarbital and between 4 and 10 to 1 for ethanol. Marijuana is also far less addictive and far less subject to abuse than many drugs now used as muscle relaxants, hypnotics, and analgesics.

The Chief legitimate concern is the effect of smoking on the lungs. Cannabis smoke carries even more tars and other particulate matter than tobacco smoke. But the amount smoked is much less, especially in medical use.  The technology Dr. Grinspoon imagined in 1995 now exists in the form of “vaporizers,” which are widely available through stores and by mail order.   (Journal of the American Medical Association, Lancet editorial, Dr. Lester Grinspoon, 1995).”

“There is indeed great concern in the medical community about the need to find better pain relief for damaged nerves, but that progress is being made (Dr. Kenneth Mackie, an associate professor in anesthesiology and physiology at the University of Washington in Seattle).”

“The use of medical cannabis has been endorsed by numerous professional organizations, including the American Academy of Family Physicians, the American Public Health Association, and the American Nurses Association. Its use is supported by such leading medical publications as The New England Journal of Medicine and the Lancet.”

    Although I’ve cited main points on pain relief through cannabis use, there is much more information with regard to the legality, use, risk and benefits of such use.  I found this brochure (referenced below) very informative where I decided it and other scientific references would be best to highlight cannabis information in a citation format.  I highly recommend you read this report in its entirety if you believe cannabis use would benefit your chronic pain problem.  Below I’ve left references for you to further your research on the topic.

Most of the citations I listed above can be found in (Chronic Pain and Medical Marijuana Brochure#888-929-4367) put out by ASA (Americans for Safe Access), Free PDF report file: http://www.safeaccessnow.org/downloads/pain_brochure.pdf.  Brochure# 888-929-4367, ASA).

You can also make inquiries by mail to: Americans for Safe Access (ASA), 1322 Webster Street, Suite 402, Oakland, California 94612.  Visit their home page for much more information on current medical marijuana use, advocacy, dispensaries, legislation, etc., at www.AmericansForSafeAccess.org, or call ASA @ 1-888-929-4367.

    Be sure to check with your state public health division laws to find out more about medical marijuana use, grow site & use rights… e.g., possible zoning grow site, use, geography restrictions, limitations, etc.   State reciprocity, card issue and federal- state law use conflicts, etc.

 Author:  Marc T. Woodard, MBA, BS Exercise Science, USA Medical Services Officer, CPT, RET.  2009 Copyright, All rights reserved.  Mirror Athlete Enterprises Publishing @: www.mirrorathlete.com, Sign up for your free eNewsletter.





Candida and What to Do About it

25 04 2008

    Some think or suspect the Candida fungus is responsible for what ails them.  Since Candida resides in us all, it is not impossible to believe this particular fungus could get out of hand.  Candida is a yeast fungus that normally is present on the skin and in the mucous membranes of the mouth, intestinal tract, and vagina, and that may become pathogenic, especially C. albicans, the causative agent of thrush (fungal infecti0n of the mouth or throat).  Infection caused by the fungus Candida albicans, is manifested by white, slightly raised patches on the mucous membrane of the tongue, mouth, and throat. The mucous membrane beneath the patches is usually raw and bleeding.  Candida overtakes your guts probiotics (read “Intestinal Bacteria & Nutrient Absorption?” at our home site), outnumbering the helpful bacteria as its food source.  Candida albicans then runs rampant within the stomach and small intestines.  When the fungus becomes present in the large intestines… This is a sign your system is fighting a battle it can’t win unless something changes. This is because your guts bacterial environment has become septic with the fungus.  With long-term infection the fungus actually sets up a root system penetrating the intestinal and mucosal lining of our guts.  Other harmful materials then are easily absorbed by this deep rooted system resulting in an immunological reaction, where the yeast syndrome impacts the entire body’s system.

 Health problems associated with this fungus – It is recognized, this deep rooted fungi system can introduce insidious pathogens in the body creating a condition where serious disease can thrive, e.g., “1) Acne or psoriasis 2) Allergies 3) Diabetes 4) Digestive disorders… Weight gain, gas, bloating, colitis (read “IBS Irritable Bowel Syndrome” at our home site) 5) Ear infections 6) Emotional upsets and depression 6) Energy imbalances or insomnia 7) Hormonal problems 8) Hyperactivity, Attention Deficit Disorder (ADD) 9) Hypoglycemia 10) Hypothyroidism 11) Lung problems 12) Obesity 13) Pollen allergies 14) Reproductive Organ Disorders 15) Sensitivities to foods, chemicals, and/or molds 16) Susceptibility to viruses, bacteria, and other infections 17) Thyroid.   Some practitioners believe that Candida overgrowth can lead to onset of chronic illnesses: Chronic fatigue symptom (CFS), fibromyalgia, Epstein-Barr virus, lupus, multiple sclerosis (MS), Alzheimer’s, Crohn’s disease, arthritis, cancer, and autism (reference, puristat com).  Once you are identified with Candida, it can take up to 7 months to remove it through proper diet.

Avoid the following foods that promote Candia thriving in the body:  All sugars, baked goods, breads, refined flour, alcohol, vinegars, pickled vegetable, dried fruits, cheeses, mushrooms.  Candida depends on sugar to survive.  Cut off the food source and you’ll starve-kill the fungus.  Also check food labels for fructose, glucose, lactose, maltose, mannitol, sorbitol and sucrose.  Avoid honey, maple syrup and molasses.  Remove processed and packaged foods from your diet (high in sugars).

Foods to consume to rid yourself of Candida:  Eat plenty of fresh fruits and veggies, whole grains, nuts and seeds, eggs, yogurt, meats, poultry, fish, oils (flaxseed, olive, sesame, and sunflower), butter, lemon, etc.  See our health store for purity products, fish oils, etc.

Author:  Marc T. Woodard, MBA, BS Exercise Science, USA Medical Services Officer, CPT, RET.  2008  Copyright.  All rights reserved, Mirror Athlete Publishing, www.mirrorathlete.com, Sign up for your Free eNewsletter.